Grant award winners since 2000
Teams & Projects 2000
Pr Nancy Miller (John Hopkins Hospital, Baltimore, USA)
Genetic factor analysis and fine family mapping of idiopathic scoliosis
Pr Masafumi Machida (Nihon University School of Medicine, Tokyo, Japan)
Melatonin study in idiopathic scoliosis
M Jeremy Fairbank M.D. (NHS Trust Oxford, United Kingdom)
Changes in the disc-vertebral body interface in idiopathic scoliosis
Pr Wafa Skalli (ENSAM – Laboratoire de biomécanique Paris, France)
Changes in the disc-vertebral body interface in idiopathic scoliosis
Teams & Projects 2001
Pr Sylvette Wiener-Vacher (Hôpital Robert Debré, Paris – France)
Predictive and prognostic value of tests assessing vestibular function in idiopathic scoliosis
Pr Alain Moreau Ph. D.(Hôpital Sainte Justine, Montreal, Canada)
Analysis of melatonin signaling pathways and molecular expression profiles in idiopathic scoliosis
Pr Martin Simoneau (Université Laval Quebec, Canada)
Role of nuchal proprioception of vestibular inputs and retinal image in updating space and constructing an egocentric frame of reference in patients with scoliotic deviation during passive and active trunk and head rotations
Pr Jack Chun Cheng (Chinese University of Hong Kong Hong Kong, China)
Relationship between postural balance, somatosensory evoked potential and progression of scoliotic deformity in adolescent idiopathic scoliosis.
Project supported jointly with the SRS
Teams & Projects 2002
Dr Jocelyne Enouf (INSERM – Hôpital Lariboisière, Paris France)
Ca2+ ATPases platelet and idiopathic scoliosis
Pr Pierre Lascombes et Pr Thierry Haumont (CHU de Nancy, Vandoeuvre-les-Nancy, France)
Prognostic value of the relative weight of sensory inputs to the balancing function in postural control in adolescents with idiopathic scoliosis
Pr Carol A. Wise, Texas Scottish Rite Hospital for Children, Dallas, USA)
Localization and analysis of genes involved in idiopathic scoliosis
Project supported jointly with the SRS
Teams & Projects 2003
Pr Nancy Miller (John Hopkins Hospital, Baltimore, USA)
Genetic analysis in familial idiopathic scoliosis
Pr Berthoz, (Collège de France, Paris, France) and Dr Dominique Rousié (Lille, France)
Adolescent idiopathic scoliosis and proprio-oculo-labyrinthine system dysfunction secondary to craniofacial asymmetry
Mr. Robert S. Pashman, M.D. (Cedars-Scoliose Sinai Medical Center Los Angeles, California, USA)
Cerebral spinal flow over concavity and vertex convexity in scoliosis
Pr. Matthew Dobbs M.D. (St.Louis Medical Center, St.Louis, USA)
Idiopathic scoliosis: genetic map and identification
Project supported jointly with the SRS
Teams & Projects 2004
Dr Christine Assaiante (CNRS Marseille, France)
Orientation control and balance strategy during ontogeny: adaptations in children and adolescents
Dr Alain Moreau (Hôpital Sainte Justine, Montreal, Canada)
Study of RPTPx tyrosine phosphatase and osteopontin in the etiopathogenesis of adolescent idiopathic scoliosis
Dr Rajasekaran (Ganga Hospital, Coimbatore, India)
Analysis of characteristic diffusions of scoliotic discs
Dr Ralph Marcucio (University of California, San Francisco, USA) et Dr Emre Acaroglu M.D. (Hacetteppe University Medical Faculty, Ankara Turkey)
Comparison of melatonin, calmodulin and 5-HT4 expression in paravertebral muscle and platelets of patients with and without idiopathic scoliosis
Project supported jointly with the SRS
Teams & Projects 2005 :
Pr Patrick Edery (Hôpital Edouard Herriot, Lyon, France)
Localization and identification of genes responsible for adolescent idiopathic scoliosis
Pr Florina Moldovan (Hôpital Sainte-Justine, Montreal, Canada)
Role of estrogen in the pathogenesis of adolescent idiopathic scoliosis
Pr Jack Chun Cheng (Chinese University of Hong Kong, China)
Longitudinal spinal growth abnormality in adolescents with idiopathic scoliosis. Morphological and functional study
Teams & Projects 2006
Pr René Castelein (University Medical Center Utrecht, Netherlands)
Etiopathogenesis of adolescent idiopathic scoliosis
Pr Matthew Dobbs (Washington University, St. Louis Medical Center,Saint-Louis , USA)
Using a zebrafish model to elucidate the generic etiology of idiopathic scoliosis.
Pr Nancy Miller (Children’s Hospital Denver, USA) and Pr Nelson Tang, (Chinese University of Hong Kong, China)
An international effort to establish a fine genetic map of IS in the chromosome area
Project supported jointly with the SRS
Teams & Projects 2007
Mr. Jeremy Fairbank and Dr Jing Yu (Nuffield Orthopaedic Centre, Oxford, United Kingdom)
Role of microfibrillar proteins in the development of scoliosis
Pr Berthoz, (Laboratoire de physiologie de la perception et de l’action, Collège de France, Paris , France) and Dr Dominique Rousié (Lille , France)
Role of cerebellar and vestibular asymmetries in adolescent idiopathic scoliosis
Pr Alain Moreau (Hôpital Sainte-Justine, Montreal, Canada)
Investigating the molecular and genetic determinants of idiopathic scoliosis: an international collaboration
Teams & Projects 2009
Pr Florina Moldovan (Hôpital Sainte-Justine, Montreal, Canada) and Pr Patrick Edery (Hôpital Edouard Herriot, Lyon, France)
Identification and validation of genes involved in adolescent IS using a combination of genetic and functional analyses
Pr Masafumi Machida (Nihon University School of Medicine, Tokyo, Japan)
Pathological mechanisms of adolescent idiopathic scoliosis morphological and functional analyses
Teams & Projects 2010
Dr Christine Assaiante (CNRS Marseille, France)
Intégration sensorielle chez les adolescents scoliotiques : du contrôle postural et moteur aux investigations cérébrales
Pr Pierre-Paul Vidal (Centre d’Etude de la Sensorimotricité, Université Paris Descartes, Paris, France)
Sensory integration in scoliotic adolescents: from postural and motor control to brain investigations
Pr Jack Chun Cheng and Pr Guo Xia (Chinese University of Hong Kong, China
Relationship between leptin bioavailability and curvature formation in idiopathic scoliosis.
Pr Martin Simoneau (Université Laval PEPS Laval , Quebec, Canada)
Quantification of vestibulospinal and reticulospinal pathway activity in adolescents with scoliosis
Teams & Projects 2011
Pr Jérôme Sales de Gauzy and Dr Pascal Swider (Toulouse, France)
The growing scoliotic spine: an unstable dynamic system?
Pr Emre Acaroglu (Ankara, Turquie), Pr Ralph Marcucio (San Francisco, Etats Unis) and Pr Florina Moldovan (Montreal, Canada)
Pr Carol Wise (TSRH, Dallas, USA) and International Genetics Scoliosis Group Meeting
Gene discovery in infantile idiopathic scoliosis
Pr Florina Moldovan (CHU Sainte Justine, Montréal, Canada) and Pr Patrick y (Hospices civils de Lyon, France)
Validation of two mutated genes in adolescent idiopathic scoliosis patients and controls by sequencing. Functional study using cellular model and morpholino approach in zebrafish
Professeur Olivier Pourquié, (Strasbourg, France)
Investigating the molecular basis of spinal deformities and idiopathic scoliosis
Teams & Projects 2012
Pr Masafumi Machida (Nihon University School of Medicine, Tokyo, Japan)
Relationship between laterality of scoliotic curvature and melatonin distribution in the cerebral hemisphere
Pr Nancy Miller (Children’s Hospital Denver, USA)
Transcriptome study in progressive adolescent idiopathic scoliosis by messenger RNA sequencing.
Teams & Projects 2013
Pr Sylvette Wiener Vacher (Hôpital Robert Debré, Paris, France)
Prognostic value of neurosensory, orthopedic and genetic markers in idiopathic scoliosis
Docteur Dominique Rousié, (Lille , France)
Study of cerebral and cerebellar interhemispheric connections in idiopathic scoliosis. Contribution of diffusion MRI
Teams & Projects 2014
Pr Pierre-Paul Vidal CESeM (Centre d’Etude de la Sensorimotricité, Université Paris Descartes, France) and Professeur Winnie Chu (Hong Kong, China)
Vestibular system in idiopathic scoliosis: link between morphology and function
Pr Christophe Destrieux and Docteur Jean-Edouard Loret (Tours, France)
Study of morphometric and functional brain abnormalities associated with adolescent idiopathic scoliosis
Teams & Projects 2015
Pr Alain Moreau (CHU Sainte Justine, Montreal, Canada)
Role of microRNAs in the etiology of adolescent idiopathic scoliosis
Dr Christine Assaiante (CNRS, Marseille, France)
Evaluation of the sense of verticality in adolescent idiopathic scoliosis
Dr Valérie Marcil (CHU Sainte Justine, Montreal, Canada)
The role of gut hormones in adolescent idiopathic scoliosis: a nutrigenomic approach
Pr Florina Moldovan (CHU Sainte Justine, Montreal, Canada)
Epigenetic, proteomic and functional study of rare variants responsible for idiopathic scoliosis
Pr Robert Carlier and Marie-Line Pissonnier (Hôpital Raymond Poincaré, Paris, France)
Contribution of muscle, high-resolution spinal and whole-body MRI techniques in early idiopathic and neuromuscular scoliosis
Teams & Projects 2016
Docteur Dominique Rousié (Lille, France)
Study of cerebral and cerebellar interhemispheric connections in IS. Contribution of diffusion MRI
Dr Guillaume Dugué (CNRS, ENS, Paris, France)
Development, validation and functional study of a mouse model of idiopathic scoliosis based on expression of a mutated form of the POC5 gene
Teams & Projects 2017
Docteur Dominique Rousié and Dr Beaudrillard (Lille, France)
Etiology of idiopathic scoliosis
Pr Wafa Skalli et Dr Claudio Vergari (Laboratoire Biomecam, Paritech, Paris)
Validation and improvement of the adolescent idiopathic scoliosis severity index
Dr Martin Simoneau (Université Laval PEPS Laval, Quebec, Canada)
Study of descending pathways in patients with adolescent idiopathic scoliosis
Pr René Castelein (University Medical Center Utrecht, Netherlands)
The pathogenic role of intervertebral collagen discs in the initiation and progression of adolescent idiopathic scoliosis
Docteur Jean-François Catanzariti (Maison de la Scoliose, SSR Centre Marc Sautelet, Villeneuve d’Ascq, France)
Evaluation of verticality in idiopathic scoliosis
Teams & Projects 2018
Pr Patrick Edery (Hospices civiles de Lyon, France), Marion Delous (CNRS Lyon), Pr Sylvie Schneider Maunoury and Dr Christine Vesque (INSERM, Morphogénèse du cerveau des vertébrés, Sorbonne, Paris, France)
Study of the role of cilia in idiopathic scoliosis
Pr Elazar Zelzer (Weizmann Institute of science, Revohot, Israel)
Idiopathic scoliosis is a neuromuscular disorder caused by a defect in the proprioceptive circuit.
Teams & Projects 2019
Pr Roger Widmann and Pr Howard J. Hillstrom (Hospital for Special Surgery, New York, USA)
Use of surface topography for screening and outcome assessment of adolescent idiopathic scoliosis
Pr Alain Moreau (CHU Sainte Justine, Montreal, Canada)
Stress-activated microRNAs in a biomechanical assay in patients with AIS
Pr Nancy Miller (Children’s Hospital Denver, USA)
Extending mechanistic findings in idiopathic scoliosis using a hypomorphic kif7 zebrafish model
Project supported jointly with the SRS
Pr Serge Zakine (Hôpital Trousseau, Paris, France) and Dr Laura Marie-Hardy (Institut du Cerveau, Paris, France)
SCOGEN: Scoliosis and genetics: deciphering the genetics of familial idiopathic scoliosis
Teams & Projects 2020
Pr Jean-François Catanzariti (Centre Marc Sautelet, Maison de la scoliose, Villeneuve d’Ascq, France)
Assessments of Cerebro-Spinal Fluid (CSF) Flow by Nuclear Magnetic Resonance (NMR) in Adolescent Idiopathic Scoliosis (AIS), and its signaling through the study of Trunk Proprioception
Pr Elie Zelzer (Weizmann Institute of Science, Israel)
The role of the proprioceptive system and PIEZO2 in the pathogenesis and recovery of idiopathic scoliosis.
Pr René Castelein (University Medical Center Utrecht, Netherlands)
22q11and scoliosis
Teams & Projects 2021
Pr Florina Moldovan (CHU Sainte Justine, Montreal, Canada)
Study of the effect of estradiol and somatomedin in polyglutamylation in cells from patients with progressive AIS.
Pr Aurélien Courvoisier (CHU Grenoble, centre alpin de la scoliose, France)
Characterization of the evolutionary patterns of Scoliotic curvatures by Analysis of displacement fields within Radiographic series (CASCARA)
Pr René Castelein, Tom Schlosse and Keita Ito (University Medical Center Utrecht, Netherlands)
Identifying patients at risk for scoliosis before disease onset: An elastographic study during growth in healthy and high-risk scoliosis populations
Project supported jointly with the SRS
Teams & Projects 2022
Dr Zhen Liu (Drum Tower Hospital, Nankin, China)
Investigating the role of gut microbiota mechanisms in idiopathic scoliosis
Pr Hervé Tostivint and Guillaume Pezeron (Museum d’Histoire Naturelle, Paris, France)
Role of urotensin-2 family peptides in spinal axis pathologies
Pr Ying Li (University of Michigan, USA)
Biological responses to titanium alloy residues using a pediatric animal model
Project supported jointly with the SRS
Teams & Projects 2023
Pr Elazar Zelzer (Weizmann Institute of science, Revohot, Israel)
Novel fibrillin-1 gene mutation may link proprioceptive function, extracellular matrix and pathogenesis of AIS
Pr Nancy Miller (Children’s Hospital Denver, USA)
A better understanding of human KIF7 gene mutations associated with AIS and estrogen responsiveness Project supported jointly with the SRS
Dr Rocio Garcia (Hôpital pour enfants de Sant Joan de Déu, Barcelona, Spain)
Study of postural, visual and vestibular disorders in patients with adolescent idiopathic scoliosis
Teams & Projects 2024
Pr Carol Wise (Texas Scottish Rite Hospital, USA)
Determining the contribution of spinal stem cells to the pathogenesis of AIS
Dr Kariman Abelin Genevois (Centre médico chirurgical des Massues, Lyon, France )
Determining the contribution of spinal stem cells to the pathogenesis of AIS
Dr Christine Vesque and Anne-Marie Tassin (Institut de Biologie, Paris, France)
Can abnormal intervertebral disc formation cause idiopathic scoliosis in the zebrafish model? If so, by what mechanisms?
Pr Ayman Assi (Faculté de médecine, Université Saint Joseph, Beyrouth, Lebanon)
Functional assessment of patients with adolescent idiopathic scoliosis
Dr Rebecca Rolfe (Zoology, School of Natural Sciences, Dublin, Ireland)
Spinal stability: study of vertebral ligaments, their development, growth and modification in scoliosis
