Pr Martin Simoneau

Université Laval, Québec, Canada
neuro-sensory, Laureate 2001, 2010 and 2017

Professor Martin Simoneau obtained his PhD in neuromechanics from Laval University in 2000, and thereafter, he was a postdoctoral fellow at Northwestern University (Chicago, IL, USA) for two years. He joined the Faculty of Medicine at Laval University following his postdoctoral training.

His research group takes a multidisciplinary approach, combining experimental approaches with sophisticated signal analysis and modeling to investigate the complex multi-component neural system involved in motor control. The laboratory focuses on sensorimotor processes that control human movement and balance and the disorders that result from damage to the central nervous system.
Their main lines of investigation aim to understand the mechanisms that control and integrate whole-body actions such as standing, walking, and reaching. They are mainly interested in how the neural processes combine sensory information from vestibular organs, eyes, muscles, and skin to select motor commands and control movement. They used various neurophysiological and psychophysical techniques to investigate fundamental human physiology and pathophysiology relevant to studying adolescent idiopathic scoliosis.

Professor Simoneau has investigated sensorimotor integration in adolescents with idiopathic scoliosis for 20 years. Through the dedicated efforts of his research team, his group has shown that alterations in sensorimotor control may contribute to the onset or progression of scoliosis. Indeed, these results suggest that altered development of descending/ascending pathways and sensorimotor areas could impair the coupling between the brain, spinal cord, and motoneurons controlling axial muscles, potentially resulting in spinal deformation during growth spurt.

Publications

References related to the assessment of the sensorimotor integration in adolescent idiopathic scoliosis patients (bold items funded by Fondation Yves Cotrel – Institut de France)

  1. Simoneau M, Mercier P, Blouin J, Allard P, Teasdale N. Altered sensory-weighting mechanisms is observed in adolescents with idiopathic scoliosis. BMC Neuroscience. 2006;7:68.
  2. Simoneau M, Richer N, Mercier P, Allard P, Teasdale N. Sensory deprivation and balance control in idiopathic scoliosis adolescent. Experimental Brain Research. 2006;170(4):576-82.
  3. Beaulieu M, Toulotte C, Gatto L, Rivard CH, Teasdale N, Simoneau M, et al. Postural imbalance in non-treated adolescent idiopathic scoliosis at different periods of progression. European Spine Journal. 2009;18(1):38-44.
  4. Simoneau M, Lamothe V, Hutin E, Mercier P, Teasdale N, Blouin J. Evidence for cognitive vestibular integration impairment in idiopathic scoliosis patients. BMC Neuroscience. 2009;10:102.
  5. Sadeghi H, Allard P, Barbier F, Gatto L, Chavet P, Rivard CH, et al. Bracing has no effect on standing balance in females with adolescent idiopathic scoliosis. Medical Science Monitor. 2008;14(6):293-8.
  6. Beaulieu M, Allard P, Simoneau M, Dalleau G, Hazime FA, Rivard CH. Relationship between oscillations about the vertical axis and center of pressure displacements in single and double leg upright stance. American Journal of Physical Medicine & Rehabilitation. 2010;89(10):809-16.
  7. Pialasse J-P, Descarreaux M, Mercier P, Blouin J, Simoneau M. Sensorimotor integration in adolescent idiopathic scoliosis patients. Recent advances in scoliosis: InTech. 2012;4: 48-70.
  8. Pialasse JP, Laurendeau S, Descarreaux M, Blouin J, Simoneau M. Is abnormal vestibulomotor responses related to idiopathic scoliosis onset or severity? Medical Hypotheses. 2013;80(3):234-6.
  9. Pialasse JP, Simoneau M. Effect of bracing or surgical treatments on balance control in idiopathic scoliosis: three case studies. The Journal of the Canadian Chiropractic Association. 2014;58(2):131-40.
  10. Pialasse JP, Descarreaux M, Mercier P, Blouin J, Simoneau M. The Vestibular-Evoked Postural Response of Adolescents with Idiopathic Scoliosis Is Altered. PLoS One. 2015;10(11):e0143124.
  11. Pialasse JP, Descarreaux M, Mercier P, Simoneau M. Sensory reweighting is altered in adolescent patients with scoliosis: Evidence from a neuromechanical model. Gait & posture. 2015;42(4):558-63.
  12. Pialasse JP, Mercier P, Descarreaux M, Simoneau M. Assessment of sensorimotor control in adults with surgical correction for idiopathic scoliosis. European Spine Journal. 2016;25(10):3347-52.
  13. Pialasse JP, Mercier P, Descarreaux M, Simoneau M. Sensorimotor Control Impairment in Young Adults With Idiopathic Scoliosis Compared With Healthy Controls. Journal of Manipulative Physiological Therapy. 2016;39(7):473-9.
  14. Pialasse JP, Mercier P, Descarreaux M, Simoneau M. A procedure to detect abnormal sensorimotor control in adolescents with idiopathic scoliosis. Gait & posture. 2017;57:124-9.
  15. Fortin C, Knoth IS, Lippé S, Pialasse J-P, Lanthier J, Bluteau C, et al. Understanding the neurophysiological mechanisms associated with balance control in adolescents with idiopathic scoliosis. Neurophysiologie Clinique. 2019;49(6):418-9.
  16. Fortin C, Pialasse J-P, Knoth IS, Lippé S, Duclos C, Simoneau M. Cortical dynamics of sensorimotor information processing associated with balance control in adolescents with and without idiopathic scoliosis. Clinical Neurophysiology. 2019;130(10):1752-61.
  17. Lanthier J, Simoneau M, Knoth IS, Lippe S, Bluteau C, Fortin C. Increased EEG alpha peak frequency in adolescents with idiopathic scoliosis during balance control in normal upright standing. Neuroscience Letters. 2020;722:134836.
  18. Simoneau M, Pialasse J-P, Mercier P, Blouin J-S. Adolescents with idiopathic scoliosis show decreased intermuscular coherence in lumbar paraspinal muscles: A new pathophysiological perspective. Clinical Neurophysiology. 2022;138:38-51.
  19. Fortin C, Sophia Knoth I, Bluteau C, Lippé S, Simoneau M. Does aberrant electrocortical dynamics pattern imply atypical balance control in adolescents with idiopathic scoliosis? Medical Hypotheses. 2024;193:1-6.